1. If the employee works from home as part of his normal contract, what on earth is ANY company data doing on the laptop, rather than being reached over VPN on a secure, shared drive? How about back-up of changed data etc.?
2. If working from home is extra to the normal working hours, sort out the resourcing, that makes this necessary, to make it unnecessary.
3. As said, data on disc can be encrypted on the fly (lucky MAC OS users have this available as standard software).
4. Many laptops now can be secured by requiring a fingerprint to enable booting.
5. As has been said, data that really must be taken off site can be on a USB memory stick that can itself be secured with passwords, encryption etc..
Too many people honestly believe that nothing on their laptop is sensitive or believe that their presentations hold nothing confidential and, if lost, can be recreated within a few hours (my partner for one), whatever you tell them, whatever horror stories they read.